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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde319f1980162a0cf42697c9c6af0452c90f103546f509f21b0425b391bb74e' 
  AND token = 'tgcrmRZJL8Hm8uiVN7JcpohZlpHT0BpDnrE1FixsbhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}