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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f4e02d6f705facec69d7e4e1dfea9d721dc9449a281eb9a0a8beaf4369df4c6' 
  AND token = 'eqbPGP1xlCSoGWspEwWPm6QTg/x0+Z5W2kxfZggK36w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}