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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8546fa1bbb137d282b18cf63fb37372283f8643d811077a893b871ae77c19bfa' 
  AND token = 's9OW1d8ExrJWAgVvH6+bTNSeSXlhYuMuGV7jWcq5OVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}