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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ba3774a8a7f54d4fb547a7affc0b071f6e3a03e5e61156df759dab3361310d' 
  AND token = 'wzrPmr2G9UuDAnAaNpqM/MEaNcVa1LVoS3GWXOxs/os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}