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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb6281b4d1a03f204747fc65f2ad0f1906b4d2821e6987933cffed6701bb5cd9' 
  AND token = 'a+ahgh6S3/uWdsL2iDa5LakUrW2rc0j8Pso4K5Zv15M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}