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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0901c3db5318d2c56f3f807a6df08bd2f73caaa1af18eef4ea86b89aed8f610a' 
  AND token = '0KnYKr4AUUyOW/V0rTb7uesAoRJRrsTN8cCD7A/Igv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}