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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01de5cfc6038646e9f0114d06d21ae2972a1aacf501794d48770c1d8620abb1' 
  AND token = 'NIy0PC0F4M2N+/T+XAfRypyacjrHdevM7HaRVsu3vZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}