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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b51d8961cd5eb71aecfa611dd53d13ef4edbad9eca2fa4697dc7dc41af10008' 
  AND token = 'aJFa/18Inv/4Bx93yDJDy94+QWpiCHhTVI8irbOW3Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}