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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3fd16fd8a2fb529dfc04e07f3f14473bc8f3a3c4a86410b9039a394f156a18' 
  AND token = '3S52fkeTkxB3OcJX/CbGgaMCNtH02xNxNJMGpd23gBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}