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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8283601f2c56ca01113bc5c3368ecaf00da066d64d8c44d50396ff9a1c7256' 
  AND token = 'r/9XeEeFHmFa7IVKAxmC0sr1wHQ4QS0RQD4NwwOxw04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}