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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0da43a0bbe677a56854a6e78272d1e0bd30670ccfc2dd3b05067929c8b229bac' 
  AND token = '/VN3EOYTY0ubPLGShLN5V3H9lCa3bjFoyVLp9M6EjQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}