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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d7bf65f47a67ec64ec6170f9914994debd920b67e29ad1b3b9e08c982e6fc2' 
  AND token = 'w2BT2hHkL1Wdh6XpLeCm3ME1XT6sE5ICb4je/Cqv8lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}