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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '911a0b640dce84eb655ded942b3a0ac7b41e13edca59397c0bcfebbdf5214e29' 
  AND token = 'l0uPysV5iz3lLebzK2UQ73MJNn24BgRgsZa5zjXalwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}