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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace5af2ad5f9351f98fe08f1f499296a45521201dd8dd6cbc189f9843c8f96cb' 
  AND token = 'agkeS2StrWT8Wrh2iSjQwBcwEudTgzLCNlesbE5tSa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}