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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7187c5f9f711e070dd9234c68d4e921831eb75f378def338ee04f81fce99d84' 
  AND token = '+zRbhunRd3PZzp+habI1qG8GERqBrRG1s08crlm2aA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}