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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2386cb98b7d35b96d71b4b46e2275a480bb4bc1128aae5499b418f40df7c046' 
  AND token = 'U3njU8/G8misWsFgZMAncln1YTyomJzykog9t898aOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}