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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc635f7c6e3396956bd682fb9a72b52982ada6196c6d4cddfe1450d3cd35ec9c' 
  AND token = 'hnM2U0Up+wsFuYLtS5qeIjAq39IMzPPD1kDWB2NS7F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}