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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186784fc61be581d4e0ebdc8a7c44f0193a69e965f22fdf1420b37b5d0baeb13' 
  AND token = 'gBTcUOwzrtD6EBefeGSmBPHs/V6Uo7T7GAYgQSF8r00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}