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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4789c2820b045dc25fbd8a048865f16c863ea1a3f06dcbf0c97dcdcee33f9c3' 
  AND token = 'chz/8E1JT2+N3pRSZaYNv36NIxby1gLMxtqK8TQA/LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}