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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fcc4a064eb0cb530143b2274ab69a4d24c94c6b3d9a265e9cbcc2b1860582e7' 
  AND token = 'rxDgcj/t2rctntaSSC0dcthQoueVYzJ42ELCwdhMUFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}