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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c4f734cdb29dc74b4256d33cec50c980d815c521b596333f03d306830af002' 
  AND token = '8HVUElEmoSTeqE5G8RYox3P12Bkfmp0zi6y31ceSynA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}