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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5a0df7419077265f55489739829c90960d63f83cc8ad6812e393d19734ed86' 
  AND token = 'mbKPtapwvDu+D+fH6kRUkCnijgvo+57cg0dJEHF/oPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}