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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5ac7fd5f2ab0bb4421b9354115e00b44be989b9df6e3dab096dcb0cbdf90f8' 
  AND token = 'Po3nxBAOV/zidwoGs0oqsCQHp1hjfXv/NqL1WcAPvdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}