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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe680cfffb0b7f45b9cab1f222d8d17e500dc7ffa52102bce2950fd890e77df0' 
  AND token = 'Sb2Qgb86/ftS3CSEx4mT6gY/wky6RV6wJ9ChNcv7wt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}