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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1cfb1b5f27f6a1c2494c30bcd3a1aac4706126670ed9bfd980ea9c797e487d' 
  AND token = 'dYeqoRF9UjVs2xtqc1b6apwzc/sW8COQ/eUgsCUWgls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}