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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb109515fb7be13768b7d5fe95e18403b8701e3c4e521be1c1523a217c41128' 
  AND token = 'kRLM8pNQOp2KWNibtfbda0tuaKUw7I72KetW/kfsXu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}