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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2412a4236447e3f2c04b049aee72700ee28548af596d3585d3f6776b19c72b9' 
  AND token = 'nh8TDhy+l4+bgaQLsi7OHv6rTN2G47nx7iTJXMCEdS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}