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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec91ec894f64620731728f60b3b3e100f108365ba4d4d07a9346f1f661714fd1' 
  AND token = 'Y4W8bw8S/D9If4vbRtE/YN23PdxJYD1tQvoyIiZ3tEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}