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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25158d43f63c2edb5f73f834794eef14baf704f0fc275b1535966f0a503ef520' 
  AND token = 'jFDC/qciLheLBLFk1FP0q8vUtxb5S09kib6WkWfzxNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}