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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657ce910964b885f4e58642a8cf6582778801cacb3e75dfd4f24731164963fc5' 
  AND token = '49UaliC94DDL4XiuYdvrCYVa9Bgit0wwB0AFsCUtELI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}