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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ca5c19291530fce530af1ddb80c1ef32d2b97388f7db0be35484d61eb0c569' 
  AND token = 'uR7j2wfYnjsLixpVq8ohzWbBtQ5DjFCHbP13WVzeL64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}