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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4b7efc32bc0f23e0f71c9da89ee74685b66b97d94f8bbf9f57b0ca83cfc4eb' 
  AND token = '9FA1VPYXDOWxkjmZmPAh7lA22GtYnwCZal9SqWIA1m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}