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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa1bd9e9c98e68bf30abdb578ee26b2819c279fe52b1153bf7d350ebff7823c' 
  AND token = 'FaAjThoO292o+h4uP3RhucmHZFsaICc79cViEGIhwbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}