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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d444f34ebf44f1f0e1819e6ab0cd331cde671c11a2418adfc5720d0a2846380' 
  AND token = '1F7MrlodSpM9o4XUK0SavruGDc7HnBLm7M7kNjr9Txo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}