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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4350cbadd7bec19fe8cdda00d572a48a32d49fde28953766ff716858b0f7ae81' 
  AND token = 'U6FD3aKcONhSwNXf6qsxsz9RktFZY9FO5Rkkfnv3Nf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}