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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0a17b136a8c3168f067e91016a02c08605a57c1ab62337331547c74c6a75356' 
  AND token = 'W2XH47f5Lk2g/eBvAbPmNIwgCN2TXZu4pmRuu3h68y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}