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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2540ec573e602d812d4430ced58e8c443c99bdada4e64f0d57e4d41d6a2a0267' 
  AND token = 'uT3SKzDu551Ua0l03Fdx279oaJ2MVDbdBYSjKUkidaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}