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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e8ab21ebcd15bc2de6ceca717a38e14ecc5eed8a81bd7d2829d893b25ab578' 
  AND token = 'dWXAXIoptdLOFzueq/ZPrb1cyOutft8D7XEcotMyoo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}