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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69940a2d848e75ce3d043aa09aebedb2d1ac4cdff8f85c0781597bf924a8f74c' 
  AND token = 'c9ZMnnYg+Kp9oxTk7Qys+AQT/v64r6H+9X1kIFJG14U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}