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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261911a36208f3eb5943ee808b660ace563e9cf62ef35adaa27bccdc0868b3ba' 
  AND token = 'Tq8Ah8HdEFs5jvmLFwg7eCND7xfJKOjPdghTg2ImOF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}