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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478f7be25c355ead9d6965b2b593a924933d0721fbf6ce2fb11c997caef7a6bb' 
  AND token = 'FF2cMK5IX9S1SPRJbyA6Z2eFDlA9+0eTR4ks4NpqGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}