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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1e949af9bc5d1ac8c34a1bed39c341a0c663358e3e9bf5f0fc313d3aeacf65' 
  AND token = 'Ad4R0Kzz4fu8ZFVTCB+PunsRUPjlv78N0GW1Vz5TQeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}