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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e22f95510c0d9f129f9aeee0d3c0c4738f11a05c75eef849282b98c131170ac' 
  AND token = '0W21Hv4Wb7Ug8cK23WrAmIhP3G50IcVEHnEO4+6W3K8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}