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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a63e9ffd5a65a2a1c60ba115be1265555a7eaaac9f60093950a96986a9d59a7' 
  AND token = 'J1dcePYdMc6BZRFA+JNhPeLF/fzU5tBrI0b+4FpbSmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}