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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8614c30802ed457ca70facbcc90a3401f3a1d7fdd03ef409e4173b7d308840' 
  AND token = 'TgHsNoWeM4RJoQZRKDlGJJCmmCidzA6oUsOSi+cI7T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}