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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca0fe30210b9c88dd18df8d972872bff7ec2b8f84dfc79173f1d06161e247da' 
  AND token = 'GCyywmeFZA949RqoIoyVAfrMCMD+IiaK+penNewXNl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}