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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420440574da31e0650b72a85a1a01619c9f64a7d1f3ee39584a21ebcf75b0461' 
  AND token = 'K6gkrhJfkt6HoDoo+vJE8eG4WUSe0WP5shRQL0RpgxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}