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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8c4960bf907c2b4337bfb6595717c03d9040e743fa6f9c2650df67efbf1b34' 
  AND token = 'pYeshkROoHhU4E4A9kvpR2f5SpRN9YckT699ObY2Asc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}