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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b97848bb289644714798aac5762c1608f56f7af775c668e94fcc7a13ec25d8f' 
  AND token = 'EnhGCoISm6g1s42Hbz1CL7w2KfqFUW104GmRXQkaeuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}