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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135259a86c7fe38fd014147b096d1651a50ef10e4126eec92cd903edd6b37135' 
  AND token = 'bX+YLIU1C4t3LQTOMaKM1Ix0VtVDglDYw47t/yIhrZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}